CD8 + T-cell marker genes reveal different immune subtypes of oral lichen planus by integrating single-cell RNA-seq and bulk RNA-sequencing

• Main Authors: Jinhao Zhang (Author), Gaoge Peng (Author), Hao Chi (Author), Jinyan Yang (Author), Xixi Xie (Author), Guobin Song (Author), Lisa Jia Tran (Author), Zhijia Xia (Author), Gang Tian (Author)
• Format: Book
• Published: BMC, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Oral lichen planus (OLP) is a local autoimmune disease induced by T-cell dysfunction that frequently affects middle-aged or elderly people, with a higher prevalence in women. CD8 + T cells, also known as killer T cells, play an important role in the progression and persistence of...