GSK3β Inhibition Prevents Macrophage Reprogramming by High-Dose Methotrexate

• Główni autorzy: Israel Ríos (Autor), Baltasar López-Navarro (Autor), Mónica Torres-Torresano (Autor), Blanca Soler Palacios (Autor), Miriam Simón-Fuentes (Autor), Ángeles Domínguez-Soto (Autor), Ittai B. Muller (Autor), Gerrit Jansen (Autor), Ángel L. Corbí (Autor), Amaya Puig-Kröger (Autor)
• Format: Książka
• Wydane: Karger Publishers, 2022-11-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Methotrexate (MTX) is an antifolate drug used as a chemotherapeutic agent for acute lymphoblastic leukemia, where MTX improves patients' prognosis. Macrophage reprogramming is being increasingly assessed as an antitumor therapeutic strategy. However, and although MTX limits the pathogenic actio...