An RNA Aptamer Targeting the Receptor Tyrosine Kinase PDGFRα Induces Anti-tumor Effects through STAT3 and p53 in Glioblastoma

Human glioblastoma (GBM) is the most aggressive malignancy of the CNS, with less than 5% survival. Despite great efforts to find effective therapeutics, current options remain very limited. To develop a targeted cancer therapeutic, we selected RNA aptamers against platelet-derived growth factor rece...

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Main Authors: Sorah Yoon (Author), Xiwei Wu (Author), Brian Armstrong (Author), Nagy Habib (Author), John J. Rossi (Author)
Format: Book
Published: Elsevier, 2019-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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