Beta amyloid differently modulate nicotinic and muscarinic receptor subtypes which regulate in vitro and in vivo the release of glycine in the rat hippocampus

• Main Authors: Stefania eZappettini (Author), Massimo eGrilli (Author), Guendalina eOlivero (Author), Elisa eMura (Author), Stefania ePreda (Author), Stefano eGovoni (Author), Alessia eSalamone (Author), Mario eMarchi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2012-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Using both in vitro (hippocampal synaptosomes in superfusion) and in vivo (microdialysis) approaches we investigated whether and to what extent β amyloid peptide 1-40 (Aβ 1-40) interferes with the cholinergic modulation of the release of glycine (GLY) in the rat hippocampus. The nicotine-evoked over...