Single nucleotide polymorphisms associated with methotrexate-induced nausea in juvenile idiopathic arthritis

• Hlavní autoři: Nini Kyvsgaard (Autor), Torben Stamm Mikkelsen (Autor), Thomas D. Als (Autor), Anne Estmann Christensen (Autor), Thomas J. Corydon (Autor), Troels Herlin (Autor)
• Médium: Kniha
• Vydáno: BMC, 2021-04-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Abstract Background Context: Methotrexate (MTX) is a cornerstone in the treatment of juvenile idiopathic arthritis (JIA). MTX treatment is commonly associated with nausea. Large inter-individual variation exists in the level of MTX-induced nausea, possibly due to genetic factors. Purpose: To investi...