Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis

• Main Authors: Alexandra Ibáñez-Escribano (Author), Cristina Fonseca-Berzal (Author), Mónica Martínez-Montiel (Author), Manuel Álvarez-Márquez (Author), María Gómez-Núñez (Author), Manuel Lacueva-Arnedo (Author), Teresa Espinosa-Buitrago (Author), Tania Martín-Pérez (Author), José Antonio Escario (Author), Penélope Merino-Montiel (Author), Sara Montiel-Smith (Author), Alicia Gómez-Barrio (Author), Óscar López (Author), José G. Fernández-Bolaños (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Herein, we report the preparation of a panel of Schiff bases analogues as antiprotozoal agents by modification of the stereoelectronic effects of the substituents on N-1 and N-4 and the nature of the chalcogen atom (S, Se). These compounds were evaluated towards Trypanosoma cruzi and Trichomonas vag...