Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis

• Egile Nagusiak: Alexandra Ibáñez-Escribano (Egilea), Cristina Fonseca-Berzal (Egilea), Mónica Martínez-Montiel (Egilea), Manuel Álvarez-Márquez (Egilea), María Gómez-Núñez (Egilea), Manuel Lacueva-Arnedo (Egilea), Teresa Espinosa-Buitrago (Egilea), Tania Martín-Pérez (Egilea), José Antonio Escario (Egilea), Penélope Merino-Montiel (Egilea), Sara Montiel-Smith (Egilea), Alicia Gómez-Barrio (Egilea), Óscar López (Egilea), José G. Fernández-Bolaños (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Herein, we report the preparation of a panel of Schiff bases analogues as antiprotozoal agents by modification of the stereoelectronic effects of the substituents on N-1 and N-4 and the nature of the chalcogen atom (S, Se). These compounds were evaluated towards Trypanosoma cruzi and Trichomonas vag...