Dectin-1/IL-15 Pathway Affords Protection against Extrapulmonary Aspergillus fumigatus Infection by Regulating Natural Killer Cell Survival

• Main Authors: Fábio S.Y. Yoshikawa (Author), Maki Wakatsuki (Author), Kosuke Yoshida (Author), Rikio Yabe (Author), Shota Torigoe (Author), Sho Yamasaki (Author), Glen N. Barber (Author), Shinobu Saijo (Author)
• Format: Book
• Published: Karger Publishers, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aspergillus fumigatus is a ubiquitous, yet potentially pathogenic, mold. The immune system employs innate receptors, such as dectin-1, to recognize fungal pathogens, but the immunological networks that afford protection are poorly explored. Here, we investigated the role of dectin-1 in anti-A. fumig...