Kinetics study of metaxalone degradation under hydrolytic, oxidative and thermal stress conditions using stability-indicating HPLC method

• Main Authors: Vamsi Krishna Marothu (Author), Rajendra N. Dash (Author), Saritha Vemula (Author), Shravani Donkena (Author), Ramesh Devi (Author), Madhavi Gorrepati (Author)
• Format: Book
• Published: Elsevier, 2012-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An isocratic stability indicating RP-HPLCâUV method is presented for the determination of metaxalone (MET) in the presence of its degradation products. The method uses Dr. Maisch C18 column (250 mmÃ4.6 mm, 5 μm) with mobile phase consisting of acetonitrileâpotassium dihydrogen orthophosphate buf...