Celecoxib Alleviates Radiation-Induced Brain Injury in Rats by Maintaining the Integrity of Blood-Brain Barrier

• Main Authors: Xiaoting Xu (Author), Hao Huang (Author), Yu Tu (Author), Jiaxing Sun (Author), Yaozu Xiong (Author), Chenying Ma (Author), Songbing Qin (Author), Wentao Hu (Author), Juying Zhou (Author)
• Format: Book
• Published: SAGE Publishing, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The underlying mechanisms of radiation-induced brain injury are poorly understood, although COX-2 inhibitors have been shown to reduce brain injury after irradiation. In the present study, the effect of celecoxib (a selective COX-2 inhibitor) pretreatment on radiation-induced injury to rat brain was...