Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine‐gingipain inhibitor COR388

Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine‐gingipain inhibitor COR388

Abstract COR388, a small‐molecule lysine‐gingipain inhibitor, is currently being investigated in a Phase 2/3 clinical trial for Alzheimer's disease (AD) with exploratory endpoints in periodontal disease. Gingipains are produced by two species of bacteria, Porphyromonas gingivalis and Porphyromo...

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Main Authors: Shirin Arastu‐Kapur (Author), Mai Nguyen (Author), Debasish Raha (Author), Florian Ermini (Author), Ursula Haditsch (Author), Joseph Araujo (Author), Ines A. M. De Lannoy (Author), Mark I. Ryder (Author), Stephen S. Dominy (Author), Casey Lynch (Author), Leslie J. Holsinger (Author)
Format: Book
Published: Wiley, 2020-02-01T00:00:00Z.
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