^99mTc-Labeled Cyclic Peptide Targeting PD-L1 as a Novel Nuclear Imaging Probe

• Main Authors: Guillermina Ferro-Flores (Author), Blanca Ocampo-García (Author), Pedro Cruz-Nova (Author), Myrna Luna-Gutiérrez (Author), Gerardo Bravo-Villegas (Author), Erika Azorín-Vega (Author), Nallely Jiménez-Mancilla (Author), Emiliano Michel-Sánchez (Author), Osvaldo García-Pérez (Author), Nancy Lara-Almazán (Author), Clara Santos-Cuevas (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent cancer therapies have focused on reducing immune suppression in the tumor microenvironment to prevent cancer progression and metastasis. PD-1 is a checkpoint protein that stops the immune response and is expressed on immune T cells. Cancer cells express a PD-1 ligand (PD-L1) to bind to the T-...