Strategies to enhance CAR-T persistence

• Main Authors: Yue Liu (Author), Lingna An (Author), Ruihao Huang (Author), Jingkang Xiong (Author), Haoyu Yang (Author), Xiaoqi Wang (Author), Xi Zhang (Author)
• Format: Book
• Published: BMC, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Chimeric antigen receptor T (CAR-T) cell therapy has significantly improved the life expectancy for patients with refractory or relapse B cell lymphoma. As for B cell acute lymphoblastic leukemia (B-ALL), although the primary response rate is promising, the high incidence of early relapse h...