Lipid Nanoparticle-Mediated Lymphatic Delivery of Immunostimulatory Nucleic Acids

Lymphatic delivery of a vaccine can be achieved using a dendritic cell (DC)-targeted delivery system that can cause DC to migrate to lymph nodes upon activation by an adjuvant. Here, we designed a mannose-modified cationic lipid nanoparticle (M-NP) to deliver the nucleic acid adjuvant, polyinosinic:...

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Bibliographic Details
Main Authors: Dongyoon Kim (Author), Yina Wu (Author), Gayong Shim (Author), Yu-Kyoung Oh (Author)
Format: Book
Published: MDPI AG, 2021-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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