Extracellular vesicles from dental pulp mesenchymal stem cells modulate macrophage phenotype during acute and chronic cardiac inflammation in athymic nude rats with myocardial infarction

• Main Authors: Elena Amaro-Prellezo (Author), Marta Gómez-Ferrer (Author), Lusine Hakobyan (Author), Imelda Ontoria-Oviedo (Author), Esteban Peiró-Molina (Author), Sonia Tarazona (Author), Pedro Salguero (Author), Amparo Ruiz-Saurí (Author), Marta Selva-Roldán (Author), Rosa Vives-Sanchez (Author), Pilar Sepúlveda (Author)
• Format: Book
• Published: BMC, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background/aims Extracellular vesicles (EVs) derived from dental pulp mesenchymal stem cells (DP-MSCs) are a promising therapeutic option for the treatment of myocardial ischemia. The aim of this study is to determine whether MSC-EVs could promote a pro-resolving environment in the heart by...