Coinjection with TLR2 agonist Pam3CSK4 reduces the pathology of leishmanization in mice.

• Main Authors: Lu Huang (Author), Meleana Hinchman (Author), Susana Mendez (Author)
• פורמט: ספר
• יצא לאור: Public Library of Science (PLoS), 2015-03-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Cutaneous leishmaniasis caused by Leishmania major is an emergent, uncontrolled public health problem and there is no vaccine. A promising prophylactic approach has been immunotherapy with Toll-like receptor (TLR) agonists to enhance parasite-specific immune responses. We have previously reported th...