Metabolomic Profiling to Identify Molecular Biomarkers of Cellular Response to Methotrexate In Vitro

• Main Authors: Ryan S. Funk (Author), Rakesh K. Singh (Author), Mara L. Becker (Author)
• Formato: Livro
• Publicado em: Wiley, 2020-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Variation in methotrexate (MTX) efficacy represents a significant barrier to early and effective disease control in the treatment of autoimmune arthritis. We hypothesize that the utilization of metabolomic techniques will allow for an improved understanding of the biochemical basis for the pharmacol...