Role of the Hedgehog Signaling Pathway in Regulating the Behavior of Germline Stem Cells

• Main Authors: Shiqin Li (Author), Meng Wang (Author), Yanghui Chen (Author), Wei Wang (Author), Junying Wu (Author), Chengpeng Yu (Author), Yuehui Zheng (Author), Zezheng Pan (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Germline stem cells (GSCs) are adult stem cells that are responsible for the production of gametes and include spermatogonial stem cells (SSCs) and ovarian germline stem cells (OGSCs). GSCs are located in a specialized microenvironment in the gonads called the niche. Many recent studies have demonst...