A fully validated microbiological assay for daptomycin injection and comparison to HPLC method

• Autori principali: Ana Paula Christ (Autore), Mariana Souto Machado (Autore), Karla Giacomelli Ribas (Autore), Alexandre Vargas Schwarzbold (Autore), Cristiane de Bona da Silva (Autore), Andréa Inês Horn Adams (Autore)
• Natura: Libro
• Pubblicazione: Universidade de São Paulo, 2015-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

abstract Daptomycin (DPT) was the first lipopeptide antibiotic available for commercialization. It is active against gram-positive bacteria, including resistant strains. This work aimed to develop and validate a turbidimetric microbiologic assay to determine daptomycin in an injectable form. A 3x3 d...