The effect of CYP2C9*2, CYP2C9*3, and VKORC1-1639 G>A polymorphism in patients under warfarin therapy in city of Kermanshah

• Päätekijät: Zohreh Hosseinkhani (Tekijä), Mona Sadeghalvad (Tekijä), Fathemeh Norooznezhad (Tekijä), Reza Khodarahmi (Tekijä), Mohammad Fazilati (Tekijä), Azadeh Mahnam (Tekijä), Ali Fattahi (Tekijä), Kamran Mansouri (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Wolters Kluwer Medknow Publications, 2018-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Polymorphism in the genes encoding CYP2C9 enzyme and VKORC1 reductase significantly influence warfarin dose requirement since patients with CYP2C9*2, CYP2C9*3 and VKORC1 mutant alleles require lower warfarin maintenance doses. Studies have reported the ethnic variations in the frequency of these gen...