Anti-miRNA103/107 encapsulated in transferrin-conjugated lipid nanoparticles crosses blood-brain barrier and reduces brain ischemic damage

• Main Authors: Pasquale Cepparulo (Author), Ornella Cuomo (Author), Virginia Campani (Author), Antonio Vinciguerra (Author), Maria Josè Sisalli (Author), Valeria Nele (Author), Serenella Anzilotti (Author), Valeria Valsecchi (Author), Antonella Casamassa (Author), Paola Brancaccio (Author), Antonella Scorziello (Author), Giuseppe De Rosa (Author), Lucio Annunziato (Author), Giuseppe Pignataro (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

MicroRNA (miRNA), by post-transcriptionally regulating the expression of genes involved in stroke response, represents important effectors in stroke pathophysiology. Recently, the 103/107 miRNA family emerged as a possible therapeutic target in stroke, as it controls the expression of sodium calcium...