Plasmatic carbonic anhydrase IX as a diagnostic marker for clear cell renal cell carcinoma

• Main Authors: Laura Lucarini (Author), Lucia Magnelli (Author), Nicola Schiavone (Author), Alfonso Crisci (Author), Alessio Innocenti (Author), Luca Puccetti (Author), Fabio Cianchi (Author), Sara Peri (Author), Claudiu T. Supuran (Author), Laura Papucci (Author), Emanuela Masini (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Carbonic anhydrase (CA, EC 4.2.1.1) IX is regarded as a tumour hypoxia marker and CA inhibitors have been proposed as a new class of antitumor agents, with one such agent in Phase II clinical trials. The expression of some CAs, in particular the isoforms CA IX and CA XII, has been correlated with tu...