Krebs Cycle Intermediates Protective against Oxidative Stress by Modulating the Level of Reactive Oxygen Species in Neuronal HT22 Cells

• Main Authors: Kenta Sawa (Author), Takumi Uematsu (Author), Yusuke Korenaga (Author), Ryuya Hirasawa (Author), Masatoshi Kikuchi (Author), Kyohei Murata (Author), Jian Zhang (Author), Xiaoqing Gai (Author), Kazuichi Sakamoto (Author), Tomoyuki Koyama (Author), Takumi Satoh (Author)
• Format: Book
• Published: MDPI AG, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Krebs cycle intermediates (KCIs) are reported to function as energy substrates in mitochondria and to exert antioxidants effects on the brain. The present study was designed to identify which KCIs are effective neuroprotective compounds against oxidative stress in neuronal cells. Here we found that...