Erythropoietin Exacerbates Inflammation and Increases the Mortality of Histoplasma capsulatum-Infected Mice

• Main Authors: Gisele Aparecida Locachevic (Author), Priscilla Aparecida Tartari Pereira (Author), Adriana Secatto (Author), Caroline Fontanari (Author), Alyne Fávero Galvão (Author), Morgana Kelly Borges Prado (Author), Karina Furlani Zoccal (Author), Tânia Petta (Author), Luiz Alberto Beraldo Moraes (Author), Simone Gusmão Ramos (Author), Fabíola Attie de Castro (Author), Carlos Artério Sorgi (Author), Lúcia Helena Faccioli (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Erythropoietin (EPO) is a key hormone involved in red blood cell formation, but its effects on nonerythroid cells, such as macrophages, have not been described. Macrophages are key cells in controlling histoplasmosis, a fungal infection caused by Histoplasma capsulatum (Hc). Considering that little...