Beta-adrenergic receptors are critical for weight loss but not for other metabolic adaptations to the consumption of a ketogenic diet in male mice

• Main Authors: Nicholas Douris (Author), Bhavna N. Desai (Author), ffolliott M. Fisher (Author), Theodore Cisu (Author), Alan J. Fowler (Author), Eleen Zarebidaki (Author), Ngoc Ly T. Nguyen (Author), Donald A. Morgan (Author), Timothy J. Bartness (Author), Kamal Rahmouni (Author), Jeffrey S. Flier (Author), Eleftheria Maratos-Flier (Author)
• Format: Book
• Published: Elsevier, 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: We have previously shown that the consumption of a low-carbohydrate ketogenic diet (KD) by mice leads to a distinct physiologic state associated with weight loss, increased metabolic rate, and improved insulin sensitivity [1]. Furthermore, we identified fibroblast growth factor 21 (FGF21)...