Achieving high immunogenicity against poliovirus with fractional doses of inactivated poliovirus vaccine in Ecuador-results from a cross-sectional serological survey

• Main Authors: Gabriel Trueba (Author), Vishali Jeyaseelan (Author), Lazaro Lopez (Author), Bernardo A. Mainou (Author), Yiting Zhang (Author), Alvaro Whittembury (Author), Alfredo Jose Olmedo Valarezo (Author), Gonzalo Baquero (Author), Rosa Romero de Aguinaga (Author), Lucia Jeannete Zurita Salinas (Author), Maria Gabriela Santacruz Mancheno (Author), Diana Elizabeth Medina Chacho (Author), Emmanuelle Quentin (Author), Ana Elena Chevez (Author), Gloria Rey-Benito (Author), Ondrej Mach (Author)
• Format: Book
• Published: Elsevier, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Background: In January 2018, Ecuador changed its routine immunization schedule by replacing one full dose of inactivated poliovirus vaccine (IPV) administered intramuscularly at 2 months of age with two doses of fractional IPV (1/5th of full dose, fIPV) administered intradermally at 2 and 4...