Association of a Lymphotoxin-α Gene Polymorphism and Atopic Asthma in Taiwanese Children

• Main Authors: Szu-Chao Huang (Author), Wen-Jun Wu (Author), Hai-Lun Sun (Author), Ko-Huang Lue (Author), Chia-Hsiu Hsu (Author), Pei-Fen Liao (Author), Min-Sho Ku (Author)
• Format: Book
• Published: Elsevier, 2008-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The lymphotoxin-α (LT-α) gene is located on chromosome 6 (6p21.1-6p21.3) and it may regulate tumor necrosis factor (TNF) production. TNF is a potent cytokine in the airway inflammatory response. Polymorphisms of TNF-associated genes have been related to asthma. This study investigated an LT-α-NcoI p...