HSP70 induces liver X receptor pathway activation and cholesterol reduction in vitro and in vivo
Objective: Heat Shock Proteins (HSPs) maintain cellular homeostasis under stress. HSP70 represents a major stress-inducible family member and has been identified as a druggable target in inherited cholesterol-sphingolipid storage diseases. We investigated if HSP70 modulates cholesterol accumulation...
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Main Authors: | Burcin Gungor (Author), Lauri Vanharanta (Author), Maarit Hölttä-Vuori (Author), Juho Pirhonen (Author), Nikolaj H.T. Petersen (Author), Silvia Gramolelli (Author), Päivi M. Ojala (Author), Thomas Kirkegaard (Author), Elina Ikonen (Author) |
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Format: | Book |
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Elsevier,
2019-10-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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