Quercetin inhibits malignant progression of high metastatic advanced colon cancer in hypoxia via suppressing ROS and PI3K/AKT pathway

• Main Authors: Pengfei Shang (Author), Jiawei Yang (Author), Lijun Shao (Author), Chao Sun (Author), Jianbo Ji (Author), Xiaoyan Wang (Author), Zongxue Zheng (Author), Xiuli Guo (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Advanced metastatic colon cancer is difficult to treat with existing chemotherapy medicines, and hypoxic microenvironment is closely related to angiogenesis and distant metastasis of colon cancer. Quercetin, a natural flavonoid, has been shown anti-tumor effects. The aim of this study is to investig...