Fn14 exacerbates acute lung injury by activating the NLRP3 inflammasome in mice

• Autores principales: Xin-Xin Guan (Autor), Hui-Hui Yang (Autor), Wen-Jing Zhong (Autor), Jia-Xi Duan (Autor), Chen-Yu Zhang (Autor), Hui-Ling Jiang (Autor), Yang Xiang (Autor), Yong Zhou (Autor), Cha-Xiang Guan (Autor)
• Formato: Libro
• Publicado: BMC, 2022-07-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Uncontrolled inflammation is an important factor in the occurrence and development of acute lung injury (ALI). Fibroblast growth factor-inducible 14 (Fn14), a plasma membrane-anchored receptor, takes part in the pathological process of a variety of acute and chronic inflammatory...