Fn14 exacerbates acute lung injury by activating the NLRP3 inflammasome in mice

• Main Authors: Xin-Xin Guan (Author), Hui-Hui Yang (Author), Wen-Jing Zhong (Author), Jia-Xi Duan (Author), Chen-Yu Zhang (Author), Hui-Ling Jiang (Author), Yang Xiang (Author), Yong Zhou (Author), Cha-Xiang Guan (Author)
• Format: Book
• Published: BMC, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Uncontrolled inflammation is an important factor in the occurrence and development of acute lung injury (ALI). Fibroblast growth factor-inducible 14 (Fn14), a plasma membrane-anchored receptor, takes part in the pathological process of a variety of acute and chronic inflammatory...