Apelin receptor inhibition in ischemia-reperfused mouse hearts protected by endogenous n-3 polyunsaturated fatty acids

• Main Authors: Shuang Zheng (Author), Weijiang Tan (Author), Xiang Li (Author), Lijing Wang (Author), Caiyi Zhu (Author), W. Glen Pyle (Author), Jianxin Chen (Author), Jian Wu (Author), Xuecong Ren (Author), Honghua Chen (Author), Yunzeng Zou (Author), Peter H. Backx (Author), Feng Hua Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: While the protective effects of n-3 polyunsaturated fatty acids (PUFAs) on cardiac ischemia-reperfusion (IR) injury have been previously reported, limited data are available regarding how these fatty acids affect membrane receptors and their downstream signaling following IR injury. We a...