Luciferase-expressing Leishmania infantum allows the monitoring of amastigote population size, in vivo, ex vivo and in vitro.

• Hauptverfasser: Grégory Michel (Verfasst von), Bernard Ferrua (Verfasst von), Thierry Lang (Verfasst von), Madhavi P Maddugoda (Verfasst von), Patrick Munro (Verfasst von), Christelle Pomares (Verfasst von), Emmanuel Lemichez (Verfasst von), Pierre Marty (Verfasst von)
• Format: Buch
• Veröffentlicht: Public Library of Science (PLoS), 2011-09-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Here we engineered transgenic Leishmania infantum that express luciferase, the objectives being to more easily monitor in real time their establishment either in BALB/c mice--the liver and spleen being mainly studied-or in vitro. Whatever stationary phase L. infantum promastigotes population--wild t...