Luciferase-expressing Leishmania infantum allows the monitoring of amastigote population size, in vivo, ex vivo and in vitro.

• Egile Nagusiak: Grégory Michel (Egilea), Bernard Ferrua (Egilea), Thierry Lang (Egilea), Madhavi P Maddugoda (Egilea), Patrick Munro (Egilea), Christelle Pomares (Egilea), Emmanuel Lemichez (Egilea), Pierre Marty (Egilea)
• Formatua: Liburua
• Argitaratua: Public Library of Science (PLoS), 2011-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Here we engineered transgenic Leishmania infantum that express luciferase, the objectives being to more easily monitor in real time their establishment either in BALB/c mice--the liver and spleen being mainly studied-or in vitro. Whatever stationary phase L. infantum promastigotes population--wild t...