Effect of Post-Polyketide Synthase Modification Groups on Property and Activity of Polyene Macrolides
The biosynthesis of polyene macrolides, which are natural products produced by soil actinomycetes, have been extensively explored, and recent studies have focused on the effects of post-polyketide synthase (PKS) modifications to polyene macrolides on toxicity, water solubility, and antifungal activi...
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