2-Phenitidine derivatives as suitable inhibitors of butyrylcholinesterase

• Main Authors: Muhammad Athar Abbasi (Author), Aziz- (Author), Muhammad Zahid Qureshi (Author), Farhan Mehmood Khan (Author), Khalid Mohmmed Khan (Author), Muhammad Ashraf (Author), Iftikhar Afzal (Author)
• Format: Book
• Published: Universidade de São Paulo, 2013-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This manuscript reports the synthesis of a series of N-substituted derivatives of 2-phenitidine. First, the reaction of 2-phenitidine (1) with benzene sulfonyl chloride (2) yielded N-(2-ethoxyphenyl) benzenesulfonamide (3), which further on treatment with sodium hydride and alkyl halides (4a-g) furn...