KBP-066A, a long-acting dual amylin and calcitonin receptor agonist, induces weight loss and improves glycemic control in obese and diabetic rats

• Main Authors: K.V. Andreassen (Author), A.T. Larsen (Author), N. Sonne (Author), K.E. Mohamed (Author), M.A. Karsdal (Author), K. Henriksen (Author)
• פורמט: ספר
• יצא לאור: Elsevier, 2021-11-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Objective: Dual amylin and calcitonin receptor agonists (DACRAs) are novel therapeutic agents that not only improve insulin sensitivity but also work as an adjunct to established T2DM therapies. DACRAs are currently administered once daily, though it is unknown whether DACRAs with increased plasma h...