The comparison of ZFNs, TALENs, and SpCas9 by GUIDE-seq in HPV-targeted gene therapy

• मुख्य लेखकों: Zifeng Cui (लेखक), Hui Liu (लेखक), Hongfeng Zhang (लेखक), Zhaoyue Huang (लेखक), Rui Tian (लेखक), Lifang Li (लेखक), Weiwen Fan (लेखक), Yili Chen (लेखक), Lijie Chen (लेखक), Sen Zhang (लेखक), Bhudev C. Das (लेखक), Konstantin Severinov (लेखक), Inga Isabel Hitzeroth (लेखक), Priya Ranjan Debata (लेखक), Zhuang Jin (लेखक), Jiashuo Liu (लेखक), Zheying Huang (लेखक), Weiling Xie (लेखक), Hongxian Xie (लेखक), Bin Lang (लेखक), Ji Ma (लेखक), Haiyan Weng (लेखक), Xun Tian (लेखक), Zheng Hu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2021-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Zinc-finger nucleases (ZFNs), transcription activator-like endonucleases (TALENs), and CRISPR-associated Cas9 endonucleases are three major generations of genome editing tools. However, no parallel comparison about the efficiencies and off-target activity of the three nucleases has been reported, wh...