Identification of SOX2 Interacting Proteins in the Developing Mouse Lung With Potential Implications for Congenital Diaphragmatic Hernia

• Main Authors: Kim A. A. Schilders (Author), Gabriëla G. Edel (Author), Evelien Eenjes (Author), Bianca Oresta (Author), Judith Birkhoff (Author), Anne Boerema-de Munck (Author), Marjon Buscop-van Kempen (Author), Panagiotis Liakopoulos (Author), Petros Kolovos (Author), Jeroen A. A. Demmers (Author), Raymond Poot (Author), Rene M. H. Wijnen (Author), Dick Tibboel (Author), Robbert J. Rottier (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Congenital diaphragmatic hernia is a structural birth defect of the diaphragm, with lung hypoplasia and persistent pulmonary hypertension. Aside from vascular defects, the lungs show a disturbed balance of differentiated airway epithelial cells. The Sry related HMG box protein SOX2 is an important t...