Silencing of CircTRIM25/miR-138-5p/CREB1 axis promotes chondrogenesis in osteoarthritis

• Main Authors: Chunlei He (Author), Zhaogan Zeng (Author), Yadong Yang (Author), Shanshan Ye (Author), Qiang Wu (Author), Xunzhi Liu (Author), Chenghong Liu (Author), Wanhui Zeng (Author), Sheng Liu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Dysregulated circular RNAs (circRNAs) are involved in osteoarthritis (OA) progression.Objective We aimed to explore the effect of hsa_circ_0044719 (circTRIM25) on the ferroptosis of chondrocytes.Methods Chondrocytes were treated with interleukin (IL)-1β to generate cell model. Cellular be...