Osteoinductivity and Antibacterial Properties of Strontium Ranelate-Loaded Poly(Lactic-co-Glycolic Acid) Microspheres With Assembled Silver and Hydroxyapatite Nanoparticles

• Main Authors: Zhenyang Mao (Author), Yang Li (Author), Yunqi Yang (Author), Zhiwei Fang (Author), Xuan Chen (Author), Yugang Wang (Author), Jian Kang (Author), Xinhua Qu (Author), Weien Yuan (Author), Kerong Dai (Author), Bing Yue (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bone-related infection rates are 4-64% in long open bone fractures and nearly 1% in joint-related surgeries. Treating bone infections and infection-related bone loss is very important. The present study prepared strontium ranelate (SR)-loaded poly(lactic-co-glycolic acid) (PLGA) microspheres (PM) wi...