Hormonal status and age differentially affect tolerance to the disruptive effects of delta-9-tetrahydrocannabinol (Δ9-THC) on learning in female rats

• Main Authors: Peter J Winsauer (Author), Catalin M Filipeanu (Author), Peter F Weed (Author), Jessie L Sutton (Author)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2015-07-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

The effects of hormone status and age on the development of tolerance to D9-THC were assessed in sham-operated (intact) or ovariectomized (OVX) female rats that received either intraperitoneal saline or 5.6 mg/kg of D9-THC daily from postnatal day (PD) 75 to 180 (early adulthood onward) or PD 35 to...