Potential of Novel Methyl Jasmonate Analogs as Anticancer Agents to Metabolically Target HK-2 Activity in Glioblastoma Cells

• Main Authors: Damla Uludağ (Author), Sadık Bay (Author), Bilgesu Onur Sucu (Author), Özgecan Şavluğ İpek (Author), Thomas Mohr (Author), Mustafa Güzel (Author), Nihal Karakaş (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Change in the energy metabolism of cancer cells, which display significant differences compared to normal cells, is a rising phenomenon in developing new therapeutic approaches against cancers. One of the metabolic enzymes, hexokinase-II (HK-II) is involved in glycolysis, and inhibiting the HK-II ac...