Severe dengue categories as research endpoints-Results from a prospective observational study in hospitalised dengue patients.

• Main Authors: Kerstin D Rosenberger (Author), Neal Alexander (Author), Eric Martinez (Author), Lucy C S Lum (Author), Carl-Erik Dempfle (Author), Thomas Junghanss (Author), Bridget Wills (Author), Thomas Jaenisch (Author), DENCO Clinical Study Group (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Severe dengue was perceived as one clinical disease entity until the WHO 2009 classification stratified it into severe vascular leakage, severe bleeding, and severe organ dysfunction. The objectives of this study were to investigate the potential use of severe dengue categories as endpoints for inte...