Simultaneous analyses of hemodynamic and electrophysiological effects of oseltamivir along with its pharmacokinetic profile using the canine paroxysmal atrial fibrillation model

• Main Authors: Ryuichi Kambayashi (Author), Ai Goto (Author), Mayu Onozato (Author), Hiroko Izumi-Nakaseko (Author), Yoshinori Takei (Author), Akio Matsumoto (Author), Shinichi Kawai (Author), Takeshi Fukushima (Author), Atsushi Sugiyama (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Since information of antiviral drug oseltamivir on the anti-atrial fibrillation (AF) property is still limited, we assessed it using the canine paroxysmal AF model. Oseltamivir in doses of 3 and 30 mg/kg/10 min was intravenously infused to the isoflurane-anesthetized, chronic atrioventricular block...