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Design, synthesis and evaluation of genistein-polyamine conjugates as multi-functional anti-Alzheimer agents

A series of genistein-polyamine conjugates (4a-4h) were designed, synthesized and evaluated as multi-functional anti-Alzheimer agents. The results showed that these compounds had significant cholinesterases (ChEs) inhibitory activity. Compound 4b exhibited the strongest inhibition to acetylcholinest...

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Bibliographic Details
Main Authors:	Xin Zhang (Author), Jiang Wang (Author), Chen Hong (Author), Wen Luo (Author), Chaojie Wang (Author)
Format:	Book
Published:	Elsevier, 2015-01-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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