Design, synthesis and evaluation of genistein-polyamine conjugates as multi-functional anti-Alzheimer agents

A series of genistein-polyamine conjugates (4a-4h) were designed, synthesized and evaluated as multi-functional anti-Alzheimer agents. The results showed that these compounds had significant cholinesterases (ChEs) inhibitory activity. Compound 4b exhibited the strongest inhibition to acetylcholinest...

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Main Authors: Xin Zhang (Author), Jiang Wang (Author), Chen Hong (Author), Wen Luo (Author), Chaojie Wang (Author)
Format: Book
Published: Elsevier, 2015-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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