Combined inflammatory and metabolic defects reflected by reduced serum protein levels in patients with Buruli ulcer disease.

• Main Authors: Richard O Phillips (Author), Fred S Sarfo (Author), Jordi Landier (Author), Reid Oldenburg (Author), Michael Frimpong (Author), Mark Wansbrough-Jones (Author), Kabiru Abass (Author), William Thompson (Author), Mark Forson (Author), Arnaud Fontanet (Author), Fatoumata Niang (Author), Caroline Demangel (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Buruli ulcer is a skin disease caused by Mycobacterium ulcerans that is spreading in tropical countries, with major public health and economic implications in West Africa. Multi-analyte profiling of serum proteins in patients and endemic controls revealed that Buruli ulcer disease down-regulates the...