Phenotypic Features of Circulating Leukocytes from Non-human Primates Naturally Infected with Trypanosoma cruzi Resemble the Major Immunological Findings Observed in Human Chagas Disease.

• Prif Awduron: Renato Sathler-Avelar (Awdur), Danielle Marquete Vitelli-Avelar (Awdur), Armanda Moreira Mattoso-Barbosa (Awdur), Marcelo Perdigão- (Awdur), Ronaldo Peres Costa (Awdur), Silvana Maria Elói-Santos (Awdur), Matheus de Souza Gomes (Awdur), Laurence Rodrigues do Amaral (Awdur), Andréa Teixeira-Carvalho (Awdur), Olindo Assis Martins-Filho (Awdur), Edward J Dick (Awdur), Gene B Hubbard (Awdur), Jane F VandeBerg (Awdur), John L VandeBerg (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Public Library of Science (PLoS), 2016-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

BACKGROUND:Cynomolgus macaques (Macaca fascicularis) represent a feasible model for research on Chagas disease since natural T. cruzi infection in these primates leads to clinical outcomes similar to those observed in humans. However, it is still unknown whether these clinical similarities are accom...