Peptidomimetic-based antibody surrogate for HER2

• Main Authors: Mengmeng Zheng (Author), Chunpu Li (Author), Mi Zhou (Author), Ru Jia (Author), Fengyu She (Author), Lulu Wei (Author), Feng Cheng (Author), Qi Li (Author), Jianfeng Cai (Author), Yan Wang (Author)
• Format: Book
• Published: Elsevier, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inhibition of human epidermal growth factor receptor 2 mediated cell signaling pathway is an important therapeutic strategy for HER2-positive cancers. Although monoclonal antibodies are currently used as marketed drugs, their large molecular weight, high cost of production and susceptibility to prot...