Precision-cut kidney slices (PCKS) to study development of renal fibrosis and efficacy of drug targeting ex vivo

• Main Authors: Fariba Poosti (Author), Bao Tung Pham (Author), Dorenda Oosterhuis (Author), Klaas Poelstra (Author), Harry van Goor (Author), Peter Olinga (Author), Jan-Luuk Hillebrands (Author)
• Format: Book
• Published: The Company of Biologists, 2015-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Renal fibrosis is a serious clinical problem resulting in the greatest need for renal replacement therapy. No adequate preventive or curative therapy is available that could be clinically used to target renal fibrosis specifically. The search for new efficacious treatment strategies is therefore war...