Development of synthetic high-density lipoprotein-based ApoA-I mimetic peptide-loaded docetaxel as a drug delivery nanocarrier for breast cancer chemotherapy

• المؤلفون الرئيسيون: Miaomiao Gong (مؤلف), Qi Zhang (مؤلف), Qi Zhao (مؤلف), Jiani Zheng (مؤلف), Yue Li (مؤلف), Siling Wang (مؤلف), Yue Yuan (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

In this study, a synthetic high-density lipoprotein (sHDL), peptide-based nanocarrier loaded with docetaxel (DTX) was constructed, against breast cancer. The thermodynamic and molecular dynamic analyses were conducted to examine the stability of nanoparticles synthesized from mimetic peptide 5 A and...